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Figure 6 | Microbial Cell Factories

Figure 6

From: The metabolic potential of Escherichia coli BL21 in defined and rich medium

Figure 6

Simplified model of transcriptional regulation of central metabolic pathways and cellular activities. General overview (A) and details of the acetate pathway (B). The flow of metabolites including energy currency metabolites such as NAD(P)H and ATP is indicated in black. Pathway regulation by transcription and sigma factors is indicated in pink: activation (+, line ending arrow) and inhibition (−, line ending bar). Regulation of transcription and sigma factors by metabolites and low molecular weight signal molecules is indicated in blue: activation/stabilisation (+, line ending arrow) and deactivation (−, line ending bar). The list of abbreviations is found at the end of the Additional file 1: Figure S9. The construction of this simplified model of transcriptional regulation is based on data found in RegulonDB (http://regulondb.ccg.unam.mx/) [58].

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