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Figure 1 | Microbial Cell Factories

Figure 1

From: Exometabolome analysis reveals hypoxia at the up-scaling of a Saccharomyces cerevisiae high-cell density fed-batch biopharmaceutical process

Figure 1

Performance of fermentation consistency runs at the small scale (10 L) bioreactor. Run 1–8 were consistency runs carrying out at DO 12.5%. (A) Online control of process parameters, DO, air sparge rate and oxygen sparge rate, for Run 1. (B) Wet cell weight (WCW) profiles for the 8 consistency runs. (C) Broth titer of the recombinant therapeutic protein profiles for the 8 consistency runs. EFT stands for the elapsed fermentation time.

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