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Table 2 Differentially expressed genes during EXP/STA1, EXP/STA2 and STA1/STA2 comparisons during SA production a

From: Global transcriptomic analysis of an engineered Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system during shikimic acid production in rich culture medium

GO termsb

EXP/STA1

EXP/STA2

STA1/STA2

 

UP

DR

UP

DR

UP

DR

Transport

15

9

9

5

8

10

Amino acid metabolism

9

15

8

ND

16

4

Electron carrier activity

2

ND

1

ND

3

ND

Out of GOs

2

21

4

8

4

14

ATP catabolic/biosynthetic process

2

1

ND

ND

ND

ND

Nucleotide/nucleoside metabolism

6

2

1

ND

ND

2

Sulfur metabolism

2

ND

4

ND

2

ND

Stress response

1

12

2

6

5

3

Catalytic activity

1

ND

1

ND

ND

ND

Regulatory

2

7

4

7

4

4

Cell envelope

ND

5

2

7

1

4

Structural molecule activity

1

ND

1

ND

ND

ND

Lipid metabolism

ND

1

ND

ND

3

ND

Other metabolic process

ND

7

ND

5

4

6

Total gene number

43

80

37

38

50

47

  1. aBased on resultant FDR value from the RP analysis equal or less to 0.05 [15]; b Biological functions were assigned according to the EcoCyc database for E. coli strain MG1655 and broadly grouped on the basis of GO terms [17]. ND, Non-detected.