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Figure 5 | Microbial Cell Factories

Figure 5

From: Differential proteomic profiling reveals regulatory proteins and novel links between primary metabolism and spinosad production in Saccharopolyspora spinosa

Figure 5

Spinosad biosynthesis enzymes detected in the total proteome. (A) Number of identified peptides for the 54 proteins that participated in spinosad biosynthesis. The proteins were subdivided into five clusters according to their functions, as indicated by the colored bars on the right: polyketide biosynthesis, rhamnose biosynthesis, forosamine biosynthesis, polyketide bridging, and other proteins. The total peptides of a unique protein was indicated at the bottom of the panel. (B) Abundance trends for the 19 semi-quantified proteins based on their PAI values, the dynamics of the individual proteins, and the average PAI of each functional cluster, which are shown on the right (the thick lines presented the an average PAI of all proteins in the different clusters).

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