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Figure 3 | Microbial Cell Factories

Figure 3

From: Decrease of UPR- and ERAD-related proteins in Pichia pastoris during methanol-induced secretory insulin precursor production in controlled fed-batch cultures

Figure 3

Global view on the ERAD and UPR responses of P. pastoris X-33 during secretory insulin precursor production (after shift from glycerol batch to methanol fed-batch). (Identified) proteins related to UPR and ERAD responses, their function, cellular location and abundance changes during secretory insulin precursor production are indicated. The green arrows (↓) indicate the identified proteins with decreasing abundance, with one arrow indicating small (log2 change 0.6-1) and two arrows strong decreases in abundance (log2 change 1–4).

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Microbial Cell Factories

ISSN: 1475-2859

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