Figure 3

Ratjadone A inhibits HIV p24 expression in MT-2-infected cells. MT-2 cells were infected with HIV_LAI and treated with ratjadone A or leptomycin B. 48 h after infection cells were fixed and stained for HIV-p24 protein (green signals) and with DAPI (blue signals). Not infected and infected but untreated cells were used as negative and positive controls respectively. (A) non-infected cells. (B) p24 distribution in infected cells without drugs. (C) p24 distribution in infected cells treated with ratjadone A, and (D) p24 distribution in infected cells treated with leptomycin B.