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Table 2 The top ten gene ontology (GO) terms identified within four pairwise comparisons

From: Transcription analysis of recombinant industrial and laboratory Saccharomyces cerevisiae strains reveals the molecular basis for fermentation of glucose and xylose

Comparison

Regulation

GO accession

GO term

n

%

p-value

MA-R4 xylose/glucose (C1)

Up

GO:0050896

Response to stimulus

174

67.4

5.60E-06

  

GO:0006950

Response to stress

123

47.7

6.50E-05

  

GO:0042221

Response to chemical stimulus

95

36.8

1.36E-03

  

GO:0016491

Oxidoreductase activity

79

30.6

1.14E-06

  

GO:0006091

Generation of precursor metabolites and energy

57

22.1

4.38E-05

 

Down

GO:0044424

Intracellular part

656

95.8

6.83E-04

  

GO:0005737

Cytoplasm

500

73.0

5.16E-06

  

GO:0009987

Cellular process

480

70.1

1.99E-06

  

GO:0043229

Intracellular organelle

410

59.9

5.18E-03

  

GO:0008152

Metabolic process

390

56.9

3.36E-09

  

GO:0044237

Cellular metabolic process

390

56.9

1.91E-10

  

GO:0044238

Primary metabolic process

374

54.6

3.26E-10

  

GO:0043170

Macromolecule metabolic process

321

46.9

1.52E-07

  

GO:0043283

Biopolymer metabolic process

321

46.9

7.22E-07

  

GO:0006996

Organelle organization

263

38.4

1.94E-08

MA-B4 xylose/glucose (C2)

Up

GO:0042221

Response to chemical stimulus

105

40.9

3.14E-08

  

GO:0016491

Oxidoreductase activity

93

36.2

2.78E-08

  

GO:0005975

Carbohydrate metabolic process

76

29.6

3.14E-08

  

GO:0006091

Generation of precursor metabolites and energy

61

23.7

4.64E-08

 

Down

GO:0044424

Intracellular part

852

95.9

1.17E-13

  

GO:0044464

Cell part

611

68.8

6.56E-11

  

GO:0009987

Cellular process

611

68.8

4.06E-14

  

GO:0005737

Cytoplasm

609

68.6

6.14E-06

  

GO:0043229

Intracellular organelle

534

60.1

3.13E-05

  

GO:0008152

Metabolic process

474

53.4

2.14E-11

  

GO:0044237

Cellular metabolic process

474

53.4

8.13E-20

  

GO:0044238

Primary metabolic process

457

51.5

4.88E-12

  

GO:0005634

Nucleus

404

45.5

2.87E-03

  

GO:0043170

Macromolecule metabolic process

382

43.0

1.34E-07

Xylose MA-R4/MA-B4 (C3)

Up

GO:0006520

Cellular amino acid metabolic process

26

100

3.73E-04

 

Down

ND

ND

ND

ND

ND

Glucose MA-R4/MA-B4 (C4)

Up

GO:0016491

Oxidoreductase activity

33

61.1

2.54E-05

  

GO:0006629

Lipid metabolic process

32

59.3

2.54E-05

 

Down

ND

ND

ND

ND

ND

  1. Up- and down-regulated gene ontology (GO) terms identified within four comparisons C1-C4. n is the number of the genes with the specified function, % is the percentage of the genes in the comparison with the specified function, and p-value is the binomial distribution probability. If no significantly over-represented GO terms were found, this was indicated by “ND” for “not detected”.