Skip to main content
Figure 3 | Microbial Cell Factories

Figure 3

From: Non-recombinant display of the B subunit of the heat labile toxin of Escherichia coli on wild type and mutant spores of Bacillus subtilis

Figure 3

Characterization of the immune response. A Th1-like immunity was induced in BALB/c mice following administration of LTB-adsorbed spores. Anti-LTB IgG1 (A) and IgG2a (B) levels detected in mice; reciprocal endpoint titers are shown. Antigen-specific IFN-γ levels secreted in vitro from spleen (C) and MLN cells (D); data are reported after subtracting the cytokine values detected in the absence of antigen stimulation. Bars represent median values. Results are representative of two independent experiments. *, P < 0.05; **, P < 0.01; ***, P < 0.001.

Back to article page