From: Role of commensal and probiotic bacteria in human health: a focus on inflammatory bowel disease
Disease | Disbiosis | Model | Technique | Sample | N | Reference |
---|---|---|---|---|---|---|
Obesity | ↓ Bacteroidetes | Mice C57BL/6J | 16S RNA sequencing | Distal intestinal content | 5088 sequences | [39] |
↑ Firmicutes | ||||||
↑ Firmicutes | Humans | 16S RNA sequencing | Faecal | 12 | [40] | |
Real time PCR | 40 | [41] | ||||
↑ Bacteroidetes | ||||||
16S RNA sequencing | 154 | [42] | ||||
↑ H2-producing bacterial groups (Prevotellaceae family and certain groups of Firmicutes) | Humans | 16S RNA sequencing | Faecal | 9 | [43] | |
Type 1 diabetes | Ratio bacteriodietes/firmicutes altered | Non obese diabetic mice (NOD) | 16S RNA sequencing | Faecal | [44] | |
Type 2 diabetes | ↓ Prevotella, | Humans | 16S RNA sequencing Real time PCR | Faecal | 36 | [45] |
↓ Bifidobacterium spp | ||||||
↓ F. prausnitzii | ||||||
16S RNA sequencing Real time PCR DGGE | 28 | [46] | ||||
↑ Bacteroides |