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Table 1 Some examples of disbiosis found in obesity and diabetes

From: Role of commensal and probiotic bacteria in human health: a focus on inflammatory bowel disease

Disease Disbiosis Model Technique Sample N Reference
Obesity Bacteroidetes Mice C57BL/6J 16S RNA sequencing Distal intestinal content 5088 sequences [39]
↑ Firmicutes
Firmicutes Humans 16S RNA sequencing Faecal 12 [40]
Real time PCR 40 [41]
↑ Bacteroidetes
16S RNA sequencing 154 [42]
↑ H2-producing bacterial groups (Prevotellaceae family and certain groups of Firmicutes) Humans 16S RNA sequencing Faecal 9 [43]
Type 1 diabetes Ratio bacteriodietes/firmicutes altered Non obese diabetic mice (NOD) 16S RNA sequencing Faecal   [44]
Type 2 diabetes Prevotella, Humans 16S RNA sequencing Real time PCR Faecal 36 [45]
  ↓ Bifidobacterium spp      
  ↓ F. prausnitzii      
    16S RNA sequencing Real time PCR DGGE   28 [46]
  ↑ Bacteroides