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Table 1 Summary of xylose fermentations by E. coli WL204

From: Homofermentative production of optically pure L-lactic acid from xylose by genetically engineered Escherichia coli B

Xylose (g L-1) Cell growth Lactic acid Volumetric productivity (g L-1h-1) Specific productivity (g g-1h-1) By-product (Acetic acid) (g L-1)
Mass (g L-1) Rate1)(h-1) Titer (g L-1) Yield2)(%) Maximum3) Average4) Maximum3) Average4)
70 (LB) 1.619 ± 0.112 0.271 ± 0.032 62.04 ± 0.92 97 1.631 ± 0.039 0.780 ± 0.017 1.05 ± 0.032 0.623 ± 0.097 1.01 ± 0.383
100 (LB) 1.901 ± 0.110 0.291 ± 0.030 66.03 ± 1.51 90 1.934 ± 0.011 1.092 ± 0.010 1.02 ± 0.054 0.653 ± 0.052 0.992 ± 0.087
70 (NBS) 2.487 ± 0.150 0.205 ± 0.020 42.9 ± 0.80 91 0.768 ± 0.021 0.358 ± 0.012 0.309 ± 0.018 0.144 ± 0.010 0.596 ± 0.026
  1. 1) The growth rate was calculated from the log growth period (0 h to 12 h).
  2. 2) The yield was calculated based on lactic acid produced over xylose metabolized.
  3. 3) The maximum productivity was calculated from the fastest 24 h fermentation period (6 h to 30 h for both 70 g L-1 and 100 g L-1 xylose LB medium; 0 h to 24 h for 70 g L-1 xylose NBS medium).
  4. 4) The average productivity was calculated from the active production period (0 h to 78 h for 70 g L-1 xylose fermentation; 0 h to 60 h for 100 g L-1xylose fermentation, 0 h to 120 h for 70 g L-1 xylose NBS fermentation).