Figure 1

The pathway for 1,2-Propanediol (1,2-PDO) production from CO ₂ in Synechococcus elongatus PCC 7942. A) Light reaction of photosynthesis generates ATP and reducing equivalents NADPH, which power the CO₂ fixation through Calvin cycle and the synthetic 1,2-PDO production pathway. gldA, yqhD and mgsA are from E.coli. Secondary alcohol dehydrogenases (sADHs) are from C. beijerinckii and T. brockii. DHAP, dihydroxyacetone phosphate. GAP, glyceraldehyde-3-phosphate. F6P, fructose-6-phophate. B) Two possible pathways for 1,2-Propanediol synthesis from methylglyoxal.