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Table 1 Highlighted benefits of methanol/sorbitol co-feeding, T = 25°C, and D = 0.023 h-1

From: A quantitative study of methanol/sorbitol co-feeding process of a Pichia pastoris Mut+/pAOX1-lacZ strain

 

Methanol

Methanol/sorbitol 0.50/0.50 C-mol/C-mol

Unit

Specific oxygen consumption

4.8 ± 0.5

3.7 ± 0.4

mmol/(g DCW · h)

Specific heat production

0.67 ± 0.07

0.51 ± 0.06

Watts/g DCW

Specific activity of β-galactosidase

7.8 ± 0.7

8.6 ± 0.8

×103 Miller unit

Theoretical maximum biomass

1.1 ~ 1.4*

1.5 ~ 1.8*

×102 g DCW

  1. * Assume maximum OTR = 600 mmol/(L · h).
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Microbial Cell Factories

ISSN: 1475-2859

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