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Table 1 Number of histidine kinases, response regulators and mis-Predicted TCS proteins present in the Streptomyces species sequenced to date*

From: Two-component systems in Streptomyces: key regulators of antibiotic complex pathways

Organism

Histidine

Response

Mis-Predicted

 

Kinase (HK)

Regulator (RR)

TCS protein**

Streptomyces bingchenggensis BCW-1

125

117

7

Streptomyces scabeiei 87.22

108

95

2

Streptomyces violaceusniger Tu 4113

106

99

1

Streptomyces coelicolor A3(2)

100

87

1

Streptomyces avermitilis MA-4680

91

72

2

Streptomyces griseus NBRC 13350

83

80

0

Streptomyces sp. Sirex AA-E

76

73

2

Streptomyces flavogriseus ATCC33331

74

64

1

Streptomyces cattleya NRRL 8057

63

59

0

Streptomyces hygroscopicus 5008

61

75

5

  1. * Taken from the P2CS database (http://www.p2cs.org/) [72, 73].
  2. **mis-Predicted TCS proteins indicates all the TCS proteins missed in the original genome annotation and later identified from DNA ORFs prediction [73].