Table 3 Melanin and L-tyrosine production in bioreactor cultures with mineral medium supplemented with glucose as carbon source*
From: Metabolic engineering of Escherichia coli to optimize melanin synthesis from glucose
Final biomass concentration (gDCW/L) | μ | qsubstrate | qTyr | qMel | YTyr/Substrate | YMel/Substrate | Final L-tyrosine concentration | Final melanin concentration | |
|---|---|---|---|---|---|---|---|---|---|
(h-1) | (g/gDCW · h) | (gTyr/gDCWh) | (gMel/gDCW · h) | (gTyr/gSub) | (gMel/gSub) | (gTyr/L) | (gMel/L) | ||
VH33GTR | 8.077 ± 0.34 | 0.112 ± 0.00 | 0.130 ± 0.02 | 0.013 ± 0.00 | N.D. | 0.155 ± 0.00 | N.D. | 9.026 ± 0.16 | N.D. |
VH33MGTR | 8.417 ± 0.05 | 0.129 ± 0.01 | 0.140 ± 0.00 | 0.013 ± 0.00 | 0.004 ± 0.00 | 0.100 ± 0.01 | 0.093 ± 0.01 | 4.152 ± 0.05 | 3.223 ± 0.35 |