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Figure 6 | Microbial Cell Factories

Figure 6

From: Investigating the effects of perturbations to pgi and eno gene expression on central carbon metabolism in Escherichia coli using 13 C metabolic flux analysis

Figure 6

Effect of perturbed eno gene expression on metabolic flux in E. coli . All fluxes were normalized to the specific glucose uptake rate of 100 to allow comparison of the flux distributions at different glucose uptake rates. Metabolic flux distributions of the eno expression-controllable strain YUEC01 in the presence of 50 μg/mL IPTG (a), 200 μg/mL IPTG (b), and 500 μg/mL IPTG (c), and the control strain YUEC00 (d) are shown. As for the reversible reactions, net fluxes are shown. G6P, glucose-6-phosphate; F6P, fructose-6-phosphate; FBP, fructose-1,6-bisphosphate; GAP, glyceraldehyde-3-phosphate; PGA, 3-phosphoglycerate; PEP, phosphoenolpyruvate; Pyr, pyruvate; AcCoA, acetyl-CoA; IsoCit, isocitrate; Mal, malate; Oxa, oxaloacetate; 6PG, 6-phosphogluconate.

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