Figure 2
From: Packaging protein drugs as bacterial inclusion bodies for therapeutic applications
Recombinant bacteria are conventionally exploited to produce soluble proteins for both Biotechnological and Pharmaceutical industries. Alternatively, recombinant bacteria can be observed as protein production-packaging factories whose products are nanostructured proteinaceous entities formed by functional species (IBs). Despite their limitations, IBs show a spectrum of properties that make them appealing as immobilized catalysts and as biocompatible materials in tissue engineering. The revealing of the therapeutic potential of bacterial IBs as nanopills for protein replacement cell therapy expands the opportunities for the development and tailoring of IBs as desired bioproducts with commercial value.