Mosaic CEN.PK113-7D genome. CEN.PK chromosomes colored by their identity to S. cerevisiae genomes, which were divided into the groups: laboratory (lab) (FL100:PRJNA60147, S288C:PRJNA128, Sigma1278b:PRJNA39317), industrial (e.g. wine, beer, bio-ethanol) (AWRI1631:PRJNA30553, AWRI796:PRJNA48559, CBS7960:PRJNA60391, CLIB382:PRJNA60145, EC1118:PRJEA37863, FostersB:PRJNA48569, FostersO:PRJNA48567, JAY291:PRJNA32809, Kyokai no. 7:PRJNA45827, Lalvin QA23:PRJNA48561, M22:PRJNA28815, PW5:PRJNA60181, RM11-1a:PRJNA13674, T73:PRJNA60195, UC5:PRJNA60197, Vin13:PRJNA48563, VL3:PRJNA48565, YJM269:PRJNA60389) and other (CLIB215:PRJNA60143, CLIB324:PRJNA60415, EC9-8:PRJNA73985, T7:PRJNA60387, Y10:PRJNA60201, YJM789:PRJNA13304, YPS163:PRJNA28813) (Additional file 12: Table S7). Each group was assigned one of the color channels of the RGB figure (red: lab, green: other and blue: industrial). The genome was divided in non-overlapping fragments of 1000 base pairs, represented by one pixel in the figure, which were aligned to the available S. cerevisiae genomes in GenBank (Additional file 12: Table S7). The identity of the best alignment in a group was set to be the value of the corresponding color channel. These values were scaled between 0 and 1; 0 meaning a maximal identity of 97% or lower, 1 meaning a maximal identity of 100%. For example, a white pixel color means 100% conservation of the fragment in all three groups. Blue and cyan mean conservation in industrial strains, but not in laboratory strains.