Figure 6From: De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnologyBiotin biosynthesis characterization in CEN.PK113-7D and S288C. A) Biotin biosynthesis pathway in CEN.PK113-7D. B) Southern blotting of S288C and CEN.PK113-7D chromosomes using specific probes for BIO1 and BIO6 genes. C) Maximal specific growth rate of CEN.PK113-7D and S288C in shake flask cultivations with synthetic medium [62] in absence (white bar), and presence (grey bar) of biotin. Growth rates were calculated from biomass measurements expressed as optical density measured at 660 nm.Back to article page