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Table 5 Metabolites of known level changes in comparison to carbon-limiting condition

From: The metabolic response of P. putida KT2442 producing high levels of polyhydroxyalkanoate under single- and multiple-nutrient-limited growth: Highlights from a multi-level omics approach

 

CN-limitation

N-limitation

Entner-Doudoroff-pathway

  

Glucose

up

up

2-Keto-3-deoxy-6Pgluconate

up

n.d.

3-Phosphoglycerate

up

n.d.

TCA cycle

  

Citrate

up

up

2-Ketoglutarate

down

down

Succinate

up

down

Fumarate

up

down

Malate

up

down

Amino acids

  

Aspartate

down

down

Cysteine

up

n.d.

Glutamate

down

down

Glutamine

up

up

Glycine

up

up

Isoleucine

up

n.d.

Ornithine

n.d.

down

Serine

n.d.

up

Threonine

n.d.

up

Tyrosine

up

down

Valine

up

up

  1. n.d., Not defined