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Table 7 Functional classification of cell cycle-regulated genes in both strainsa

From: Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain

  

Strain

NRRL2338

Px

COG

Functional categories

% COG probesets

% Probesets with q-value < = 0.001

% Probesets with q-value < = 0.001

I

Cellular processes and signaling

   

I.1

Cell cycle control, cell division, chromosome partitioning

0,35

0,99

0,69

I.2

Cell motility

0,01

0

0

I.3

Cell wall/membrane/envelope biogenesis

2,05

3,22

3,81

I.4

Defense mechanisms

0,89

0,00

0,87

I.5

Intracellular trafficking, secretion, and vesicular transport

0,24

0,25

0,69

I.6

Posttranslational modification, protein turnover, chaperones

1,90

5,94

3,99

I.7

Signal transduction mechanisms

1,91

0,99

1,91

II

Information storage and processing

   

II.1

Amino acid transport and metabolism

0,01

0

0

II.2

Cell wall/membrane/envelope biogenesis

0,01

0

0

II.3

Chromatin structure and dynamics

0,01

0

0

II.4

General function prediction only

0,30

0,50

0,35

II.5

Nucleotide transport and metabolism

0,07

0

0

II.6

Posttranslational modification, protein turnover, chaperone

0,04

0

0

II.7

Replication, recombination and repair

2,44

0,74

2,43

II.8

RNA processing and modification

0,01

0

 

II.9

Secondary metabolites biosynthesis, transport catabolism

0,04

0

 

II.10

Signal transduction mechanisms

0,71

0,50

0,69

II.11

Transcription

7,20

2,23

3,29

II.12

Translation, ribosomal structure and biogenesis

2,48

4,21

10,75

III

Metabolism

   

III.l

Amino acid transport and metabolism

6,60

0

8,15

III.2

Carbohydrate transport and metabolism

6,08

7,67

6,59

III.3

Cell wall/membrane/envelope biogenesis

0,38

0

0,17

III.4

Coenzyme transport and metabolism

2,63

5,20

4,33

III.5

Energy production and conversion

4,79

9,90

8,15

III.6

Inorganic ion transport and metabolism

2,68

4,21

2,25

III.7

Lipid transport and metabolism

4,24

2,72

5,03

III.8

Nucleotide transport and metabolism

1,27

2,97

3,64

III.9

Posttranslational modification, protein turnover, chaperones

0,08

0

0,17

III.10

Secondary metabolites biosynthesis, transport catabolism

2,90

2,48

2,77

III. 11

Signal transduction mechanisms

0,16

0

0

IV

Poorly characterized

   

IV.1

Function unknown

32,11

27,23

22,70

IV.2

General function prediction only

7,37

8,17

6,59

 

Total probesets

7060

404

577

  1. aThe categories over-represented and under-represented are evidenced, respectively, by BOLD and oblique number