Table 4 Variations within genes related to transcription and translation processes

SACE_2076

148

nusB

Frameshift

(-G 316)

NusB antiterminator factor No paralogue.

Transcription factors

SACE 0891

206

Frameshift (+G 581/582)

TetR family transcriptional regulator

SACE_1040

163

Missense (R30C)

MarR family transcriptional regulator

SACE_1895

281

Frameshift (+C 603/604)

XRE family transcriptional regulator

SACE_2927

918

Missense (P52L)

SARP family transcriptional regulator

SACE_3079

294

Frameshift

(-C 506)

LysR family transcriptional regulator

SACE_3348

96

Missense (E60A)

XRE family transcriptional regulator

SACE_4500

233

Frameshift

(-C 129; -G 222)

GntR family transcriptional regulator

SACE_4536

327

Missense (T246N, L249M)

Lacl family transcription regulator

SACE_4775

246

Missense (A96V)

MerR family transcriptional regulator

SACE_5410

287

Missense (P140F)

XRE family transcriptional regulator

SACE_5425

505

Missense and in frame deletion (V297S, V298W, A299R, V300C, Q301R A302P, H303R, D304-, G305R)

PucR- family transcriptional regulator

SACE_5448-

SACE_5449

126

150

Duplication of SACE_5448 and SACE_5449

SACE_5448: Unknown function SACE 5449: LuxR family transcriptional regulator

SACE_5739

282

Missense (K206T)

XRE family transcriptional regulator

SACE_6021

484

Frameshift (+A 1212/1213)

PucR- family transcriptional regulator

Signal transduction

SACE_1833

241

Frameshift (-C 667)

Two-component system response regulator

SACE_1879

587

Frameshift (+C 1002/1003)

Serine/threonine protein kinase

SACE_1988

150

Missense (G125D)

Universal stress protein UspA

SACE_2583

541

Nonsense (R478*)

N-acyl D-amino acid deacylase

SACE_4937

414

Missense (G30R)

Mandelate racemase/starvation sensing protein

SACE_5284

286

staP

IPM

Endonuclease/Exonuclease/Phosphatase family protein

SACE_5286

224

Frameshift (-G419, -G 430)

Two-component system response regulator

SACE_5301

533

Frameshift (+C 1585/1586)

N-acyl_D-amino acid deacylase

SACE 6086

879

kdpD

Missense (P828L)

Osmosensitive K+ channel histidine kinase

SACE_6447

228

mtrA

In frame deletion (VI96-, HI97-)

Two-component system response regulator

SACE_6490

424

Missense

(S37R)

Two-component system sensor kinase

SACE_6720

526

phoD

Missense (C328Y, P382F)

Phosphodiesterase/alkaline phosphatase D (phosphate starvation)

SACE_7263

382

Missense (A222T)

Two-component system sensor kinase

Translation machinery

SACE_0443

464

cysS

Missense (G198S)

Cysteinyl-tRNA synthetase

SACE_0799

593

metS

Missense (P569S)

Methionyl-tRNA synthetase

SACE_2075

188

efp

Frameshift (+C 504)

Elongation factor P

SACE_3403

474

gatA

Missense (A243E)

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit

SACE_5926

1027

infB

Missense (A278V)

Translation initiation factor 2

SACE_5919

536

Frameshift (-G 821)

Pseudouridine synthase

Protein turnover and chaperones

SACE_1339

860

IPM

Aminopeptidase N

SACE_2951

174

clpC

Frameshift (+G 468/469)

ATPases with chaperone activity, ATP-binding subunit

SACE_3756

768

clpA

Missense (I284T)

ATPases with chaperone activity, ATP-binding subunit

SACE_6784

610

Frameshift (-C 1573)

Molecular chaperone

SACE_6113

481

IPM?

Aminopeptidase