Figure 5

Visualization of the LAP algorithm results on the two chromosome strands independently analyzed. Comparison between the transcriptional profiling of all the 6494 S. erythraea genes in phase A versus phase B in the NRRL2338 strain(A) and in the Px strain(B) is shown. A q value of 0,01 and a fold change of 0,5 were chosen as filtering parameters. The transcriptionally up-modulated regions are shown in RED while the down- modulated are in GREEN. The OriC is indicated as O and the resolution of the chromosome is 1 Mb. The core region is evidenced in blue and the non-core region in orange; the position of clusters involved in the secondary metabolism, erythromycin production and coding for ribosomal proteins are outlined by arrows.