TY - JOUR AU - Koopman, Frank AU - Beekwilder, Jules AU - Crimi, Barbara AU - van Houwelingen, Adele AU - Hall, Robert D. AU - Bosch, Dirk AU - van Maris, Antonius JA AU - Pronk, Jack T. AU - Daran, Jean-Marc PY - 2012 DA - 2012/12/08 TI - De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae JO - Microbial Cell Factories SP - 155 VL - 11 IS - 1 AB - Flavonoids comprise a large family of secondary plant metabolic intermediates that exhibit a wide variety of antioxidant and human health-related properties. Plant production of flavonoids is limited by the low productivity and the complexity of the recovered flavonoids. Thus to overcome these limitations, metabolic engineering of specific pathway in microbial systems have been envisaged to produce high quantity of a single molecules. SN - 1475-2859 UR - https://doi.org/10.1186/1475-2859-11-155 DO - 10.1186/1475-2859-11-155 ID - Koopman2012 ER -