TY - CHAP AU - Doig SB, F. AU - Lye, G. L. ED - Ratledge CK, B. PY - 2006 DA - 2006// TI - High throughput screening and process optimisation BT - Basic Biotechnology ID - Doig SB2006 ER - TY - JOUR AU - Baneyx, F. PY - 1999 DA - 1999// TI - Recombinant protein expression in Escherichia coli JO - Curr Opin Biotech VL - 10 UR - https://doi.org/10.1016/S0958-1669(99)00003-8 DO - 10.1016/S0958-1669(99)00003-8 ID - Baneyx1999 ER - TY - JOUR AU - Weickert, M. J. AU - Doherty, D. H. AU - Best, E. A. AU - Olins, P. O. PY - 1996 DA - 1996// TI - Optimization of heterologous protein production in Escherichia coli JO - Curr Opin Biotech VL - 7 UR - https://doi.org/10.1016/S0958-1669(96)80051-6 DO - 10.1016/S0958-1669(96)80051-6 ID - Weickert1996 ER - TY - JOUR AU - Hust, M. AU - Steinwand, M. AU - Al-Halabi, L. AU - Helmsing, S. AU - Schirrmann, T. AU - Dubel, S. PY - 2009 DA - 2009// TI - Improved microtitre plate production of single chain Fv fragments in Escherichia coli JO - New Biotechnol VL - 25 UR - https://doi.org/10.1016/j.nbt.2009.03.004 DO - 10.1016/j.nbt.2009.03.004 ID - Hust2009 ER - TY - JOUR AU - Donovan, R. S. AU - Robinson, C. W. AU - Glick, B. R. PY - 1996 DA - 1996// TI - Review: optimizing inducer and culture conditions for expression of foreign proteins under the control of the lac promoter JO - J Ind Microbiol VL - 16 UR - https://doi.org/10.1007/BF01569997 DO - 10.1007/BF01569997 ID - Donovan1996 ER - TY - JOUR AU - Makrides, S. C. PY - 1996 DA - 1996// TI - Strategies for achieving high-level expression of genes in Escherichia coli JO - Microbiol Rev VL - 60 ID - Makrides1996 ER - TY - JOUR AU - Duetz, W. A. PY - 2007 DA - 2007// TI - Microtiter plates as mini-bioreactors: miniaturization of fermentation methods JO - Trends Microbiol VL - 15 UR - https://doi.org/10.1016/j.tim.2007.09.004 DO - 10.1016/j.tim.2007.09.004 ID - Duetz2007 ER - TY - JOUR AU - Schapper, D. AU - Alam, M. N. AU - Szita, N. AU - Eliasson Lantz, A. AU - Gernaey, K. V. PY - 2009 DA - 2009// TI - Application of microbioreactors in fermentation process development: a review JO - Anal Bioanal Chem VL - 395 UR - https://doi.org/10.1007/s00216-009-2955-x DO - 10.1007/s00216-009-2955-x ID - Schapper2009 ER - TY - JOUR AU - Hermann, R. AU - Lehmann, M. AU - Buchs, J. PY - 2003 DA - 2003// TI - Characterization of gas–liquid mass transfer phenomena in microtiter plates JO - Biotechnol Bioeng VL - 81 UR - https://doi.org/10.1002/bit.10456 DO - 10.1002/bit.10456 ID - Hermann2003 ER - TY - JOUR AU - Betts, J. I. AU - Baganz, F. PY - 2006 DA - 2006// TI - Miniature bioreactors: current practices and future opportunities JO - Microb Cell Fact VL - 5 UR - https://doi.org/10.1186/1475-2859-5-21 DO - 10.1186/1475-2859-5-21 ID - Betts2006 ER - TY - JOUR AU - Bareither, R. AU - Pollard, D. PY - 2011 DA - 2011// TI - A Review of Advanced Small-Scale Parallel Bioreactor Technology for Accelerated Process Development: Current State and Future Need JO - Biotechnol Progr VL - 27 UR - https://doi.org/10.1002/btpr.522 DO - 10.1002/btpr.522 ID - Bareither2011 ER - TY - JOUR AU - Jourdier, E. AU - Poughon, L. AU - Larroche, C. AU - Monot, F. AU - Chaabane, F. B. PY - 2012 DA - 2012// TI - A new stoichiometric miniaturization strategy for screening of industrial microbial strains: application to cellulase hyper-producing Trichoderma reesei strains JO - Microb Cell Fact VL - 11 UR - https://doi.org/10.1186/1475-2859-11-70 DO - 10.1186/1475-2859-11-70 ID - Jourdier2012 ER - TY - JOUR AU - Ge, X. AU - Hanson, M. AU - Shen, H. AU - Kostov, Y. AU - Brorson, K. A. AU - Frey, D. D. AU - Moreira, A. R. AU - Rao, G. PY - 2006 DA - 2006// TI - Validation of an optical sensor-based high-throughput bioreactor system for mammalian cell culture JO - J Biotechnol VL - 122 UR - https://doi.org/10.1016/j.jbiotec.2005.12.009 DO - 10.1016/j.jbiotec.2005.12.009 ID - Ge2006 ER - TY - JOUR AU - Puskeiler, R. AU - Kaufmann, K. AU - Weuster-Botz, D. PY - 2005 DA - 2005// TI - Development, parallelization, and automation of a gas-inducing milliliter-scale bioreactor for high-throughput bioprocess design (HTBD) JO - Biotechnol Bioeng VL - 89 UR - https://doi.org/10.1002/bit.20352 DO - 10.1002/bit.20352 ID - Puskeiler2005 ER - TY - JOUR AU - Ahn, W. S. AU - Ahn, J. Y. AU - Jung, C. H. AU - Hwang, K. Y. AU - Kim, E. E. AU - Kim, J. AU - Im, H. AU - Kim, J. O. AU - Yu, M. H. AU - Lee, C. PY - 2007 DA - 2007// TI - Optimization of expression conditions for soluble protein by using a robotic system of multi-culture vessels JO - J Microbiol Biotechnol VL - 17 ID - Ahn2007 ER - TY - JOUR AU - Funke, M. AU - Diederichs, S. AU - Kensy, F. AU - Muller, C. AU - Buchs, J. PY - 2009 DA - 2009// TI - The baffled microtiter plate: increased oxygen transfer and improved online monitoring in small scale fermentations JO - Biotechnol Bioeng VL - 103 UR - https://doi.org/10.1002/bit.22341 DO - 10.1002/bit.22341 ID - Funke2009 ER - TY - JOUR AU - Anderlei, T. AU - Zang, W. AU - Buchs, J. PY - 2004 DA - 2004// TI - Online respiration activity measurement (OTR, CTR, RQ) in shake flasks JO - Biochem Eng J VL - 17 UR - https://doi.org/10.1016/S1369-703X(03)00181-5 DO - 10.1016/S1369-703X(03)00181-5 ID - Anderlei2004 ER - TY - JOUR AU - Wittmann, C. AU - Kim, H. M. AU - John, G. AU - Heinzle, E. PY - 2003 DA - 2003// TI - Characterization and application of an optical sensor for quantification of dissolved O2 in shake-flasks JO - Biotechnol Lett VL - 25 UR - https://doi.org/10.1023/A:1022402212537 DO - 10.1023/A:1022402212537 ID - Wittmann2003 ER - TY - JOUR AU - Kensy, F. AU - Zimmermann, H. F. AU - Knabben, I. AU - Anderlei, T. AU - Trauthwein, H. AU - Dingerdissen, U. AU - Buchs, J. PY - 2005 DA - 2005// TI - Oxygen transfer phenomena in 48-well microtiter plates: Determination by optical monitoring of sulfite oxidation and verification by real-time measurement during microbial growth JO - Biotechnol Bioeng VL - 89 UR - https://doi.org/10.1002/bit.20373 DO - 10.1002/bit.20373 ID - Kensy2005 ER - TY - JOUR AU - Puskeiler, R. AU - Kusterer, A. AU - John, G. T. AU - Weuster-Botz, D. PY - 2005 DA - 2005// TI - Miniature bioreactors for automated high-throughput bioprocess design (HTBD): reproducibility of parallel fed-batch cultivations with Escherichia coli JO - Biotechnol Appl Biochem VL - 42 UR - https://doi.org/10.1042/BA20040197 DO - 10.1042/BA20040197 ID - Puskeiler2005 ER - TY - JOUR AU - Huber, R. AU - Ritter, D. AU - Hering, T. AU - Hillmer, A. K. AU - Kensy, F. AU - Muller, C. AU - Wang, L. AU - Buchs, J. PY - 2009 DA - 2009// TI - Robo-Lector - a novel platform for automated high-throughput cultivations in microtiter plates with high information content JO - Microb Cell Fact VL - 8 UR - https://doi.org/10.1186/1475-2859-8-42 DO - 10.1186/1475-2859-8-42 ID - Huber2009 ER - TY - JOUR AU - Knorr, B. AU - Schlieker, H. AU - Hohmann, H. -. P. AU - Weuster-Botz, D. PY - 2007 DA - 2007// TI - Scale-down and parallel operation of the riboflavin production process with Bacillus subtilis JO - Biochem Eng J VL - 33 UR - https://doi.org/10.1016/j.bej.2006.10.023 DO - 10.1016/j.bej.2006.10.023 ID - Knorr2007 ER - TY - JOUR AU - Zimmermann, H. F. AU - Degussa, J. R. PY - 2006 DA - 2006// TI - A Fully Automated Robotic System for High Throughput Fermentation JO - J Assoc Lab Automation VL - 11 UR - https://doi.org/10.1016/j.jala.2006.03.003 DO - 10.1016/j.jala.2006.03.003 ID - Zimmermann2006 ER - TY - JOUR AU - Samorski, M. AU - Muller-Newen, G. AU - Buchs, J. PY - 2005 DA - 2005// TI - Quasi-continuous combined scattered light and fluorescence measurements: a novel measurement technique for shaken microtiter plates JO - Biotechnol Bioeng VL - 92 UR - https://doi.org/10.1002/bit.20573 DO - 10.1002/bit.20573 ID - Samorski2005 ER - TY - JOUR AU - Kensy, F. AU - Zang, E. AU - Faulhammer, C. AU - Tan, R. K. AU - Buchs, J. PY - 2009 DA - 2009// TI - Validation of a high-throughput fermentation system based on online monitoring of biomass and fluorescence in continuously shaken microtiter plates JO - Microb Cell Fact VL - 8 UR - https://doi.org/10.1186/1475-2859-8-31 DO - 10.1186/1475-2859-8-31 ID - Kensy2009 ER - TY - JOUR AU - Park, J. H. AU - Lee, S. Y. PY - 2010 DA - 2010// TI - Metabolic pathways and fermentative production of L-aspartate family amino acids JO - Biotechnol J VL - 5 UR - https://doi.org/10.1002/biot.201000032 DO - 10.1002/biot.201000032 ID - Park2010 ER - TY - BOOK AU - Eggeling, L. AU - Bott, M. PY - 2005 DA - 2005// TI - Handbook of Corynebacterium glutamicum PB - CRC Press CY - Boca Raton, FL UR - https://doi.org/10.1201/9781420039696 DO - 10.1201/9781420039696 ID - Eggeling2005 ER - TY - JOUR AU - Billman-Jacobe, H. AU - Wang, L. AU - Kortt, A. AU - Stewart, D. AU - Radford, A. PY - 1995 DA - 1995// TI - Expression and secretion of heterologous proteases by Corynebacterium glutamicum JO - Appl Environ Microb VL - 61 ID - Billman-Jacobe1995 ER - TY - JOUR AU - Meissner, D. AU - Vollstedt, A. AU - van Dijl, J. AU - Freudl, R. PY - 2007 DA - 2007// TI - Comparative analysis of twin-arginine (Tat)-dependent protein secretion of a heterologous model protein (GFP) in three different Gram-positive bacteria JO - Appl Microbiol Biot VL - 76 UR - https://doi.org/10.1007/s00253-007-0934-8 DO - 10.1007/s00253-007-0934-8 ID - Meissner2007 ER - TY - JOUR AU - Teramoto, H. AU - Watanabe, K. AU - Suzuki, N. AU - Inui, M. AU - Yukawa, H. PY - 2011 DA - 2011// TI - High yield secretion of heterologous proteins in Corynebacterium glutamicum using its own Tat-type signal sequence JO - Appl Microbiol Biot VL - 91 UR - https://doi.org/10.1007/s00253-011-3281-8 DO - 10.1007/s00253-011-3281-8 ID - Teramoto2011 ER - TY - JOUR AU - Kikuchi, Y. AU - Itaya, H. AU - Date, M. AU - Matsui, K. AU - Wu, L. -. F. PY - 2008 DA - 2008// TI - Production of Chryseobacterium proteolyticum protein-glutaminase using the twin-arginine translocation pathway in Corynebacterium glutamicum JO - Appl Microbiol Biot VL - 78 UR - https://doi.org/10.1007/s00253-007-1283-3 DO - 10.1007/s00253-007-1283-3 ID - Kikuchi2008 ER - TY - JOUR AU - Date, M. AU - Itaya, H. AU - Matsui, H. AU - Kikuchi, Y. PY - 2006 DA - 2006// TI - Secretion of human epidermal growth factor by Corynebacterium glutamicum JO - Lett Appl Microbiol VL - 42 UR - https://doi.org/10.1111/j.1472-765X.2005.01802.x DO - 10.1111/j.1472-765X.2005.01802.x ID - Date2006 ER - TY - JOUR AU - Degering, C. AU - Eggert, T. AU - Puls, M. AU - Bongaerts, J. AU - Evers, S. AU - Maurer, K. H. AU - Jaeger, K. E. PY - 2010 DA - 2010// TI - Optimization of Protease Secretion in Bacillus subtilis and Bacillus licheniformis by Screening of Homologous and Heterologous Signal Peptides JO - Appl Environ Microb VL - 76 UR - https://doi.org/10.1128/AEM.01146-10 DO - 10.1128/AEM.01146-10 ID - Degering2010 ER - TY - JOUR AU - Brockmeier, U. AU - Caspers, M. AU - Freudl, R. AU - Jockwer, A. AU - Noll, T. AU - Eggert, T. PY - 2006 DA - 2006// TI - Systematic screening of all signal peptides from Bacillus subtilis: a powerful strategy in optimizing heterologous protein secretion in Gram-positive bacteria JO - J Mol Biol VL - 362 UR - https://doi.org/10.1016/j.jmb.2006.07.034 DO - 10.1016/j.jmb.2006.07.034 ID - Brockmeier2006 ER - TY - JOUR AU - David, F. AU - Westphal, R. AU - Bunk, B. AU - Jahn, D. AU - Franco-Lara, E. PY - 2010 DA - 2010// TI - Optimization of antibody fragment production in Bacillus megaterium: The role of metal ions on protein secretion JO - J Biotechnol VL - 150 UR - https://doi.org/10.1016/j.jbiotec.2010.07.023 DO - 10.1016/j.jbiotec.2010.07.023 ID - David2010 ER - TY - JOUR AU - Kottmeier, K. AU - Muller, C. AU - Huber, R. AU - Buchs, J. PY - 2010 DA - 2010// TI - Increased product formation induced by a directed secondary substrate limitation in a batch Hansenula polymorpha culture JO - Appl Microbiol Biot VL - 86 UR - https://doi.org/10.1007/s00253-009-2285-0 DO - 10.1007/s00253-009-2285-0 ID - Kottmeier2010 ER - TY - JOUR AU - Nealon, A. J. AU - Willson, K. E. AU - Pickering, S. C. AU - Clayton, T. M. AU - O'Kennedy, R. D. AU - Titchener-Hooker, N. J. AU - Lye, G. J. PY - 2005 DA - 2005// TI - Use of operating windows in the assessment of integrated robotic systems for the measurement of bioprocess kinetics JO - Biotechnol Progr VL - 21 UR - https://doi.org/10.1021/bp049868+ DO - 10.1021/bp049868+ ID - Nealon2005 ER - TY - JOUR AU - van Ooyen, J. AU - Noack, S. AU - Bott, M. AU - Reth, A. AU - Eggeling, L. PY - 2012 DA - 2012// TI - Improved L-lysine production with Corynebacterium glutamicum and systemic insight into citrate synthase flux and activity JO - Biotechnol Bioeng VL - 109 UR - https://doi.org/10.1002/bit.24486 DO - 10.1002/bit.24486 ID - van Ooyen2012 ER - TY - JOUR AU - Gourdon, P. AU - Lindley, N. D. PY - 1999 DA - 1999// TI - Metabolic analysis of glutamate production by Corynebacterium glutamicum JO - Metab Eng VL - 1 UR - https://doi.org/10.1006/mben.1999.0122 DO - 10.1006/mben.1999.0122 ID - Gourdon1999 ER - TY - JOUR AU - Blombach, B. AU - Schreiner, M. AU - Bartek, T. AU - Oldiges, M. AU - Eikmanns, B. PY - 2008 DA - 2008// TI - Corynebacterium glutamicum tailored for high-yield L-valine production JO - Appl Microbiol Biot VL - 79 UR - https://doi.org/10.1007/s00253-008-1444-z DO - 10.1007/s00253-008-1444-z ID - Blombach2008 ER - TY - JOUR AU - Litsanov, B. AU - Kabus, A. AU - Brocker, M. AU - Bott, M. PY - 2012 DA - 2012// TI - Efficient aerobic succinate production from glucose in minimal medium with Corynebacterium glutamicum JO - Microb Biotechnol VL - 5 UR - https://doi.org/10.1111/j.1751-7915.2011.00310.x DO - 10.1111/j.1751-7915.2011.00310.x ID - Litsanov2012 ER - TY - JOUR AU - Weuster-Botz, D. AU - Kelle, R. AU - Frantzen, M. AU - Wandrey, C. PY - 1997 DA - 1997// TI - Substrate Controlled Fed-Batch Production of l-Lysine with Corynebacterium glutamicum JO - Biotechnol Progr VL - 13 UR - https://doi.org/10.1021/bp970034j DO - 10.1021/bp970034j ID - Weuster-Botz1997 ER - TY - JOUR AU - Keilhauer, C. AU - Eggeling, L. AU - Sahm, H. PY - 1993 DA - 1993// TI - Isoleucine synthesis in Corynebacterium glutamicum: molecular analysis of the ilvB-ilvN-ilvC operon JO - J Bacteriol VL - 175 ID - Keilhauer1993 ER - TY - JOUR AU - von der Osten, C. H. AU - Gioannetti, C. AU - Sinskey, A. J. PY - 1989 DA - 1989// TI - Design of a defined medium for growth of Corynebacterium glutamicum in which citrate facilitates iron uptake JO - Biotechnol Lett VL - 11 UR - https://doi.org/10.1007/BF01026778 DO - 10.1007/BF01026778 ID - von der Osten1989 ER - TY - JOUR AU - Hallborn, J. AU - Carlsson, R. PY - 2002 DA - 2002// TI - Automated screening procedure for high-throughput generation of antibody fragments JO - Biotechniques VL - 33 ID - Hallborn2002 ER - TY - JOUR AU - Kondragunta, B. AU - Drew, J. L. AU - Brorson, K. A. AU - Moreira, A. R. AU - Rao, G. PY - 2010 DA - 2010// TI - Advances in Clone Selection Using High-Throughput Bioreactors JO - Biotechnol Progr VL - 26 ID - Kondragunta2010 ER - TY - JOUR AU - Wenk, P. AU - Hemmerich, J. AU - Müller, C. AU - Kensy, F. PY - 2012 DA - 2012// TI - High-Throughput Bioprocess Development in Shaken Microbioreactors JO - Chem-Ing-Tech VL - 84 UR - https://doi.org/10.1002/cite.201100206 DO - 10.1002/cite.201100206 ID - Wenk2012 ER - TY - JOUR AU - Huber, R. AU - Scheidle, M. AU - Dittrich, B. AU - Klee, D. AU - Buchs, J. PY - 2009 DA - 2009// TI - Equalizing growth in high-throughput small scale cultivations via precultures operated in fed-batch mode JO - Biotechnol Bioeng VL - 103 UR - https://doi.org/10.1002/bit.22349 DO - 10.1002/bit.22349 ID - Huber2009 ER - TY - JOUR AU - Panula-Perala, J. AU - Siurkus, J. AU - Vasala, A. AU - Wilmanowski, R. AU - Casteleijn, M. G. AU - Neubauer, P. PY - 2008 DA - 2008// TI - Enzyme controlled glucose auto-delivery for high cell density cultivations in microplates and shake flasks JO - Microb Cell Fact VL - 7 UR - https://doi.org/10.1186/1475-2859-7-31 DO - 10.1186/1475-2859-7-31 ID - Panula-Perala2008 ER - TY - JOUR AU - Siurkus, J. AU - Panula-Perala, J. AU - Horn, U. AU - Kraft, M. AU - Rimseliene, R. AU - Neubauer, P. PY - 2010 DA - 2010// TI - Novel approach of high cell density recombinant bioprocess development: Optimisation and scale-up from microlitre to pilot scales while maintaining the fed-batch cultivation mode of E. coli cultures JO - Microb Cell Fact VL - 9 UR - https://doi.org/10.1186/1475-2859-9-35 DO - 10.1186/1475-2859-9-35 ID - Siurkus2010 ER - TY - JOUR AU - Huber, R. AU - Palmen, T. G. AU - Ryk, N. AU - Hillmer, A. K. AU - Luft, K. AU - Kensy, F. AU - Buchs, J. PY - 2010 DA - 2010// TI - Replication methods and tools in high-throughput cultivation processes - recognizing potential variations of growth and product formation by on-line monitoring JO - BMC Biotechnol VL - 10 UR - https://doi.org/10.1186/1472-6750-10-22 DO - 10.1186/1472-6750-10-22 ID - Huber2010 ER - TY - JOUR AU - Riesenberg, D. AU - Menzel, K. AU - Schulz, V. AU - Schumann, K. AU - Veith, G. AU - Zuber, G. AU - Knorre, W. A. PY - 1990 DA - 1990// TI - High cell density fermentation of recombinant Escherichia coli expressing human interferon alpha 1 JO - Appl Microbiol Biot VL - 34 UR - https://doi.org/10.1007/BF00170927 DO - 10.1007/BF00170927 ID - Riesenberg1990 ER - TY - JOUR AU - Funke, M. AU - Buchenauer, A. AU - Schnakenberg, U. AU - Mokwa, W. AU - Diederichs, S. AU - Mertens, A. AU - Muller, C. AU - Kensy, F. AU - Buchs, J. PY - 2010 DA - 2010// TI - Microfluidic BioLector-Microfluidic Bioprocess Control in Microtiter Plates JO - Biotechnol Bioeng VL - 107 UR - https://doi.org/10.1002/bit.22825 DO - 10.1002/bit.22825 ID - Funke2010 ER - TY - JOUR AU - Eikmanns, B. J. AU - Kleinertz, E. AU - Liebl, W. AU - Sahm, H. PY - 1991 DA - 1991// TI - A family of Corynebacterium glutamicum/Escherichia coli shuttle vectors for cloning, controlled gene expression, and promoter probing JO - Gene VL - 102 UR - https://doi.org/10.1016/0378-1119(91)90545-M DO - 10.1016/0378-1119(91)90545-M ID - Eikmanns1991 ER - TY - JOUR AU - Yawalkar, A. A. AU - Heesink, A. B. M. AU - Versteeg, G. F. AU - Pangarkar, V. G. PY - 2008 DA - 2008// TI - Gas–liquid Mass Transfer Coefficient in Stirred Tank Reactors JO - Can J Chem Eng VL - 80 UR - https://doi.org/10.1002/cjce.5450800507 DO - 10.1002/cjce.5450800507 ID - Yawalkar2008 ER - TY - JOUR AU - Van‘t Riet, K. PY - 1983 DA - 1983// TI - Mass transfer in fermentation JO - Trends Biotechnol VL - 1 UR - https://doi.org/10.1016/0167-7799(83)90034-3 DO - 10.1016/0167-7799(83)90034-3 ID - Van‘t Riet1983 ER - TY - JOUR AU - Winkler, U. K. AU - Stuckmann, M. PY - 1979 DA - 1979// TI - Glycogen, hyaluronate, and some other polysaccharides greatly enhance the formation of exolipase by Serratia marcescens JO - J Bacteriol VL - 138 ID - Winkler1979 ER -