Table 6 Transcription factors involved in central carbon metabolism uniquely identified for S. cerevisiae
ORF | Name | Description |
|---|---|---|
YDR123C | INO2 | Positive regulatory required for depression of the phospholipid biosynthetic enzymes, regulated by OPI1. |
YOL108C | INO4 | |
YOR344C | SGC1 | Serine-rich protein binding E-boxes of glycolytic genes and contributes to their activation. Has been found to suppress the gcr1 requirement for enolase, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase, phosphoglycerate mutase, and pyruvate kinase gene expression. It is necessary for maximal enolase expression |
YKL038W | RGT1 | Transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose. |
YGL209W | MIG2 | Regulatory protein, involved in glucose repression of the SUC genes. |
YER028C | MIG3 | Transcriptional repressor controlled by Snf1 involved in controlling the transcription of SIR genes. Also involved in the response to toxic agents. |
YLR373C | VID22 | Glycosylated integral membrane protein involved in fructose-1,6-bisphosphatase (FBPase) transport and degradation. |
YDR255C | RMD5 | Conserved protein involved in the degradation of the gluconeogenic enzyme fructose-1,6-bisphosphatase; also required for sporulation. Negative regulator of gluconeogenesis. |
YJL103C | GSM1 | Putative zinc cluster protein of unknown function; proposed to be involved in the regulation of energy metabolism. |