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Figure 5 | Microbial Cell Factories

Figure 5

From: Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae

Figure 5

α-Santalene titers in a two-phase partitioned glucose limited aerobic chemostat. α-Santalene (bottom) and farnesol (top) titers expressed in mg l-1 and Cmmol l-1 (the C-molar weight of α-santalene and farnesol are respectively 13.62 and 14.82 g Cmol-1). Strains SCIGS28 (tHMG1↑), SCIGS29 (+ P HXT1 -ERG9, lpp1 Δ), SCIGS30 (+ dpp1 Δ) were cultivated at dilution rate D = 0.05 h-1 and D = 0.1 h-1. Strains SCIGS31 (+ gdh1 Δ), SCIGS24 (+ERG20, GDH2↑), SCIGS25 (+ upc2-1, tHMG1↑) were cultivated at dilution rate D = 0.05 h-1. Error bars represent the standard deviation from three independent cultivations.

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