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Figure 3 | Microbial Cell Factories

Figure 3

From: Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae

Figure 3

Sesquiterpene productivity in a two-phase partitioned glucose-limited aerobic chemostat. α-Santalene and farnesol production rate in Cmmol (g biomass)-1 h-1 (the C-molar weight of α-santalene and farnesol are, respectively, 13.62 and 14.82 g Cmol-1). (A) Strains SCIGS28 (tHMG1↑), SCIGS29 (+ P HXT1 -ERG9, lpp1 Δ), SCIGS30 (+ dpp1 Δ), SCIGS31 (+ gdh1 Δ), SCIGS24 (+ ERG20, GDH2↑), SCIGS25 (+ upc2-1, tHMG1↑) cultivated at dilution rate D = 0.05 h-1. (B) Strains SCIGS28 (tHMG1↑), SCIGS29 (+ P HXT1 -ERG9; lpp1 Δ), SCIGS30 (+lpp1 Δ) cultivated at dilution rate D = 0.1 h-1. Error bars represent the standard deviation from three independent cultivations.

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