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Table 1 Comparison of industrial biotechnology and chemical technology

From: New challenges and opportunities for industrial biotechnology

Items

Industrial biotechnology

Chemical technology

Reaction Time

Slow: production takes days

Fast: production takes hours

Substrates

Agricultural products

Petroleum or its derivatives

Conversion of substrates to products

Low: e.g. PHB/glucose ≈ 33 wt% PHA/fatty acids ≈ 60 wt%

High: e.g. Polyethylene/ethylene ≈ 100%

Medium

Water

Mostly organic solvents

Consumption of water

A lot

Less

Reaction conditions

30-40°C, normal pressure

Generally >100°C, High Pressures

Product concentration

Low: Several mg to 100 g/L

Very high

Product recovery cost

Very high

Low to medium

Processing

Normally discontinuous one

Can be continuous

Sterilization

Necessary

No need

Production facility cost

Very high

Low to high (explosive proof)

Waste water

Not toxic, easier to treat

Generally toxic, difficult to treat