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Figure 4 | Microbial Cell Factories

Figure 4

From: Physiological response of Pichia pastoris GS115 to methanol-induced high level production of the Hepatitis B surface antigen: catabolic adaptation, stress responses, and autophagic processes

Figure 4

Vacuole morphology changes in P. pastoris GS115 during methanol-induced high-level production of HBsAg. Time-dependent change in the percentage of cells containing large spherical vacuoles with autophagic bodies (AB, ), cells containing large spherical vacuole without autophagic bodies (○), cells containing irregular vacuoles (▴), cells with small vacuoles (Δ), cells without any visible vacuoles (), and apoptotic cells (□). The bar in the electron micrographs of representative cells corresponds to 500 nm.

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Microbial Cell Factories

ISSN: 1475-2859

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