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Figure 3 | Microbial Cell Factories

Figure 3

From: Physiological response of Pichia pastoris GS115 to methanol-induced high level production of the Hepatitis B surface antigen: catabolic adaptation, stress responses, and autophagic processes

Figure 3

Mitochondrial morphology and size changes during methanol-induced high-level production of the Hepatitis B surface antigen. Transmission electron micrographs of P. pastoris GS115 (A) at the end of the glycerol batch phase and (B) 112 hours after the onset of methanol feeding. White arrow heads indicate mitochondria. (C) Quantification of the average total mitochondrial area within the cross sectional average cell area. The vertical bars encompass individual cell variance, e.g. the lowest and highest total mitochondrial area observed in a single cell in each growth phase; (left column) at the end of the glycerol batch phase and (right column) 112 hours after the onset of methanol feeding.

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Microbial Cell Factories

ISSN: 1475-2859

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