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Figure 3 | Microbial Cell Factories

Figure 3

From: From transcriptional landscapes to the identification of biomarkers for robustness

Figure 3

Transcriptional landscape graphs of three different gene clusters grouped by stress condition. Different transcriptional landscapes of K-means clustered transcriptome data were obtained and selected landscapes show the (normalized and scaled) expression level (intensity) of all genes (in light colours) within the cluster. In dark colours and indicated by markers for each condition, the average expression level for all genes in the cluster is shown. The three landscapes show the clusters-specific response to sodium hypochlorite (top), to cold stress and salt (NaCl) stress (middle), and acid stress (bottom). The first two landscapes are both consisting of two clusters that differ slightly from each other in the level of activation of gene expression. In the case of the NaCl and cold response landscape this discrimination is associated with the response to cold, for which the response of the second cluster is much higher than that of genes in the first cluster. In case of the sodium hypochlorite landscape the same effect can be observed; the response of genes in the first cluster is much higher than that of genes in the second cluster.

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