Receptor | Localization | Ligand | Origin of the ligand |
---|---|---|---|
TLR2 | Cell surface | Lipopeptides | Bacteria |
 |  | Lipoproteins | G+ bacteria |
 |  | LTA | G+ bacteria |
TLR2/1 | Cell surface | Triacylated lipopeptide | G-bacteria, mycoplasma |
TLR2/6 | Cell surface | Diacylated lipopeptides | G+ bacteria, mycoplasma |
TLR3 | Intracellular compartment | dsRNA | Viruses, virus infected cells |
TLR4/MD2 | Cell surface, intracellular compartment | LPS | G- bacteria |
TLR5 | Cell surface | Flagellin protein | Bacteria |
TLR7 | Intracellular compartment | ssRNA | Viruses |
TLR8 | Intracellular compartment | ssRNA | Viruses |
TLR9 | Intracellular compartment, cell surface | DNA | DNA viruses, bacteria |
TLR11 | Cell surface | Uropathogenic bacterial components | Uropathogenic bacteria |
NOD1 | Cell cytoplasm | Meso-DAP | PG from G-, some G+, mycobacterium |
NOD2 | Cell cytoplasm | MDP | PG from G-, G+ bacteria, mycobacterium |