Figure 3
IL-10, IL-12p70 production and the IL-10/IL-12p70 ratio by monocyte-derived dendritic cells stimulated with 20 different L. plantarum strains. The graphs were produced using data from Meijerink et al., [69] based on one of the 5 representative donors. The different strains induce striking different amounts of these cytokines. Based on the IL-12 to IL-10 ratios it is clear that these cytokines can vary independently of each other resulting in strains with distinct pro-inflammatory and anti-inflammatory profiles.