Medical nutrition therapy: use of sourdough lactic acid bacteria as a cell factory for delivering functional biomolecules and food ingredients in gluten free bread

Table 1 Clinical manifestations and related signs of celiac disease¹

Gastrointestinal Symptoms	Extraintestinal symptoms
Chronic diarrhoea	Infertility or fetal loss
Recurrent pancreaitis	Anaemia
Abdominal distension	Loss of appetite
Abdominal pain	Short stature
Duodenal obstruction	Osteomalacia/osteoporosis
Vomiting	Fatigue
Constipation	Dementia
Flautolence	Weakness (myopothy, neuropthy)
Muscle wasting	Vitamin deficiency
Steatorrhea	Type 1 diabetes
Weight loss	Hypo/hyperthyroidism
Anorexia	Alopecia areata
Bulky, sticky and pale stools	Depression
Failure to thrive	Behavioral changes
	Late-onset puberty
	Epilepsy
	Dermatitis herpetiformis
	Arthritis
	Aphthous stomatis
	Dental enamel hypoplasia
	Cerebellar ataxia
	Myelopathy
	Esophageal reflux

¹Source : Feighery (1999); Murray (1999); Fasano and Catassi (2001); (Tack et al., 2010).

ISSN: 1475-2859