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Figure 1 | Microbial Cell Factories

Figure 1

From: A cell factory of Bacillus subtilis engineered for the simple bioconversion of myo-inositol to scyllo-inositol, a potential therapeutic agent for Alzheimer's disease

Figure 1

Inositol metabolism in B. subtilis. B. subtilis iol genes encoding enzymes for reactions in the inositol catabolic pathway and the respective intermediate compounds are shown. The intermediate compounds are myo-inositol (compound 1), D-chiro-inositol (compound 2), scyllo-inositol I (compound 3), scyllo-inosose (compound 4), 1-keto-D-chiro-inositol (compound 5), 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (compound 6), 5-deoxy-D-glucuronic acid (compound 7), 2-deoxy-5-keto-D-gluconic acid (compound 8), 2-deoxy-5-keto-D-gluconic acid 6-phosphate (compound 9), dihydroxyacetone phosphate (compound 10), malonic semialdehyde (compound 11), and acetyl-CoA (compound 12).

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Microbial Cell Factories

ISSN: 1475-2859

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