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Figure 1 | Microbial Cell Factories

Figure 1

From: Virus-like particle production with yeast: ultrastructural and immunocytochemical insights into Pichia pastoris producing high levels of the Hepatitis B surface antigen

Figure 1

Images of recombinant P. pastoris growing on glycerol and methanol. Transmission electron microscopy of ultrathin sectioned cells of P. pastoris GS115 growing on (A) glycerol and (B) after 151 h growth on methanol for induction of HBsAg production. (C) Image of P. pastoris X-33 after 96 h growth on methanol for induction of secretory insulin precursor production [38]. Abbreviations: n, nucleus; v, vacuole; m, mitochondrion; r, ribosome; p, peroxisome; *, 'irregular cloud-shaped area'. The insets show close-ups of ribosomes from marked areas of respective images.

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