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Figure 4 | Microbial Cell Factories

Figure 4

From: Modeling and measuring intracellular fluxes of secreted recombinant protein in Pichia pastoris with a novel 34S labeling procedure

Figure 4

Sensitivity analysis of the extracellular Fab3H6 concentration. In each picture the effect of two different input variables on the extracellular Fab3H6 concentration is shown. The red dot in the middle represents the measured values in the chemostat. These initial values were changed from -10 to +10 fold resulting in depicted areas. In (A) t1/2 Deg and t1/2 Sec, in (B) t1/2 Sec and qPi, in (C) and (D) t1/2 Deg and qPi were analyzed. Furthermore, in (D) the maximum secretion capacity was set to 101.4 μg g-1 h-1 (2 fold of the measured value).

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