From: Statistics-based model for prediction of chemical biosynthesis yield from Saccharomyces cerevisiae
Reference | Product | Yield | Primary Step | Second Step | OVE_C2 | OVE_C3 | KNO_C2 | NUT_C2 | INT_C2 | CUL_C2 | OXY_C2 |
---|---|---|---|---|---|---|---|---|---|---|---|
[41] | (E, E, E)-Geranylgeraniol | 0.00025 | 10 | 10 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[41] | (E, E, E)-Geranylgeraniol | 0.014 | 10 | 10 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
[41] | (E, E, E)-Geranylgeraniol | 0.047 | 10 | 10 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
[41] | (E, E, E)-Geranylgeraniol | 0.018 | 10 | 10 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
[41] | (E, E, E)-Geranylgeraniol | 0.031 | 10 | 10 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
[41] | (E, E, E)-Geranylgeraniol | 0.058 | 10 | 10 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
[41] | (E, E, E)-Geranylgeraniol | 0.14 | 10 | 10 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
[42] | 1,2-Propanediol | 0.014 | 4 | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[43] | 1,2-Propanediol | 0.010 | 4 | 3 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[43] | 1,2-Propanediol | 0.026 | 4 | 3 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[44] | 5-epi-aristolochene | 0.010 | 10 | 9 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
[44] | 5-epi-aristolochene | 0.0090 | 10 | 9 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
[45] | Acetate | 0.13 | 9 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[46] | Acetate | 0.015 | 9 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[47] | Acetate | 0.26 | 9 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
[48] | Amorphadiene | 0.00049 | 12 | 9 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[48] | Amorphadiene | 0.0020 | 12 | 9 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[48] | Amorphadiene | 0.0040 | 12 | 9 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[48] | Amorphadiene | 0.011 | 12 | 9 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[48] | Amorphadiene | 0.016 | 12 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
[48] | Amorphadiene | 0.016 | 12 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
[49] | Amorphadiene | 0.0080 | 12 | 9 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[49] | Amorphadiene | 0.0090 | 12 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
[49] | Amorphadiene | 0.011 | 12 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
[49] | Amorphadiene | 0.013 | 12 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
[48] | Artemisinic acid | 0.0030 | 12 | 10 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
[48] | Artemisinic acid | 0.011 | 12 | 10 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
[50] | Cyanophycin | 0.12 | 10(0) | 2(1) | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
[50] | Cyanophycin | 0.10 | 10(0) | 2(1) | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
[50] | Cyanophycin | 0.15 | 10(0) | 2(1) | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
[51] | Dihydroxyacetone | 0.0040 | 4 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[51] | Dihydroxyacetone | 0.034 | 4 | 3 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[52] | D-Lactic acid | 0.61 | 9 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 |
[53] | Dolichol | 0.00010 | 10 | 11 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[53] | Dolichol | 0.00018 | 10 | 11 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[53] | Ergosterol | 0.00015 | 10 | 21 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[53] | Ergosterol | 0.00020 | 10 | 21 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[20] | Ethanol | 0.55 | 9 | 2 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
[20] | Ethanol | 0.47 | 8 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[54] | Ethanol | 0.080 | 8 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
[54] | Ethanol | 0.12 | 8 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[54] | Ethanol | 0.15 | 8 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[55] | Ethanol | 0.53 | 9 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[55] | Ethanol | 0.20 | 9 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[55] | Ethanol | 0.47 | 9 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[55] | Ethanol | 0.42 | 9 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[55] | Ethanol | 0.36 | 9 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[46] | Ethanol | 0.44 | 9 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[46] | Ethanol | 0.32 | 8 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
[56] | Ethanol | 0.52 | 9 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[47] | Ethanol | 0.55 | 9 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
[47] | Ethanol | 0.39 | 9 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
[47] | Ethanol | 0.51 | 9 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | 1 |
[57] | Ethylene* | 0.00069 | 13 | 10 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[44] | Farnesol | 0.036 | 10 | 9 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[58] | Flavanones | 0.030 | 10(0) | 14(3) | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[58] | Flavanones | 0.053 | 10(0) | 14(3) | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[59] | Formate | 0.00024 | 6 | 7 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[59] | Formate | 0.00030 | 6 | 7 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[60] | Geraniol | 0.00011 | 10 | 8 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[60] | Geraniol | 0.00019 | 10 | 8 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[60] | Geraniol | 0.00019 | 10 | 8 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[61] | Glycerol | 0.12 | 4 | 2 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[61] | Glycerol | 0.12 | 4 | 2 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[45] | Glycerol | 0.41 | 4 | 2 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
[45] | Glycerol | 0.45 | 4 | 2 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
[45] | Glycerol | 0.45 | 4 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[62] | Glycerol | 0.49 | 4 | 2 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
[62] | Glycerol | 0.41 | 4 | 2 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
[46] | Glycerol | 0.050 | 4 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[46] | Glycerol | 0.037 | 2 | 4 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
[63] | Glycerol | 0.45 | 4 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[63] | Glycerol | 0.54 | 4 | 2 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
[30] | Glycerol 3-phosphate | 0.0010 | 4 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 |
[64] | Hydrocortisone | 0.0020 | 10(0) | 19(2) | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
[64] | Hydrocortisone | 0.0020 | 10(0) | 19(2) | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
[64] | Hydrocortisone | 0.021 | 10(0) | 19(2) | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
[64] | Hydrocortisone | 0.026 | 10(0) | 19(2) | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
[65] | Lactate | 0.44 | 9 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[66] | Lactate | 0.21 | 9 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[67] | L-Ascorbic acid | 0.14 | 2(0) | 8(2) | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[67] | L-Ascorbic acid | 0.066 | 2(0) | 8(2) | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[60] | Linalool | 8.8 × 10-5 | 10 | 8 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[60] | Linalool | 2.3 × 10-5 | 10 | 8 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[68] | L-Lactic Acid | 0.65 | 9 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
[32] | Malate | 0.28 | 11 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
[49] | Mevalonate | 0.022 | 12 | 3 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
[49] | Mevalonate | 0.022 | 12 | 3 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
[69] | Naringenin | 0.0070 | 8(0) | 15(3) | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[69] | Naringenin | 0.0020 | 8(0) | 15(5) | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[15] | Naringenin | 0.00058 | 10 | 14 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
[70] | n-Butanol | 0.00020 | 12 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
[69] | p-Coumaric Acid | 0.033 | 8(0) | 12(2) | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[71] | p-Hydroxycinnamic acid | 0.00020 | 8 | 12 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[71] | p-Hydroxycinnamic acid | 0.20 | 8(0) | 12(2) | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[15] | Pinocembrin | 6.6 × 10-5 | 10 | 14 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
[72] | Poly[(R)-3-hydroxybutyrate] | 0.00056 | 10 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[72] | Poly[(R)-3-hydroxybutyrate] | 0.003 | 10 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[72] | Poly[(R)-3-hydroxybutyrate] | 0.012 | 10 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
[72] | Poly[(R)-3-hydroxybutyrate] | 0.00047 | 10 | 3 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[72] | Poly[(R)-3-hydroxybutyrate] | 0.0090 | 10 | 3 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[72] | Poly[(R)-3-hydroxybutyrate] | 0.018 | 10 | 3 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
[72] | Poly[(R)-3-hydroxybutyrate] | 0.0010 | 10 | 3 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[72] | Poly[(R)-3-hydroxybutyrate] | 0.017 | 10 | 3 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
[44] | Premnaspirodiene | 0.011 | 10 | 9 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
[44] | Premnaspirodiene | 0.0090 | 10 | 9 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
[73] | Pyruvate | 0.55 | 9 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[46] | Pyruvate | 0.0050 | 9 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[74] | Reticuline | 0.051 | 8(0) | 16(3) | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[75] | Ribitol | 0.0020 | 5 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[75] | Ribitol | 0.027 | 5 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[75] | Ribitol | 0.017 | 5 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[75] | Ribitol | 0.021 | 5 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[41] | Squalene | 0.042 | 10 | 9 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[76] | Taxadiene | 7.7 × 10-5 | 12 | 8 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
[77] | Vanillin | 0.0030 | 3 | 6 | 0 | 1 | 1 | 1 | 0 | 0 | 0 |
[75] | Xylitol | 0.0070 | 5 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[75] | Xylitol | 0.014 | 5 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[75] | Xylitol | 0.014 | 5 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[47] | Xylitol | 0.27 | 5 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
[47] | Xylitol | 0.29 | 5 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | 1 |
[78] | β-carotene | 4.5 × 10-7 | 10 | 14 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[78] | β-carotene | 2.9 × 10-6 | 10 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
[78] | β-carotene | 0.00011 | 10 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
[78] | β-carotene | 0.00036 | 10 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
[78] | β-carotene | 0.0010 | 10 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |