Figure 1From: Biotechnological applications of recombinant single-domain antibody fragmentsRepresentation of the single-domain antibody specific features. Single-domain antibodies can derive from different immunoglobulines. Camelid VHs and VHHs differ for four hallmark amino acid residues that are crucial for preserving the V domain stability when it is expressed paired to the VL domain or alone, respectively.Back to article page