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Figure 5 | Microbial Cell Factories

Figure 5

From: Optimization of production of the anti-keratin 8 single-chain Fv TS1-218 in Pichia pastoris using design of experiments

Figure 5

Response surface plots of the cell viability and WCW responses. Response surface plots of the optimization model showing the influence of temperature and MeOH concentration on the viability of the P. pastoris cells (A) and the effect of temperature and pH on the biomass (i.e. change of WCW in %) after 72 h of induction (B). The pH did not have a significant effect on the viability of the P. pastoris cells. The MeOH concentration of the response surface plot in panel B was at the center point level (1.25%).

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