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Figure 9 | Microbial Cell Factories

Figure 9

From: Single cell analysis applied to antibody fragment production with Bacillus megaterium: development of advanced physiology and bioprocess state estimation tools

Figure 9

Bioprocess monitoring: Productivity and Production Intensity. Product yield (YP/X) and Production Intensity measurements of B. megaterium cells producing/secreting ABF scFv D1.3 in a bioreactor cultivation (15 g/L fructose, DO>20%, 1L). A) Growth phase dependent product yield (YP/X) and production intensity of ABF D1.3 scFv production and secretion. Production intensities were determined with applying different lysozyme concentrations. B) Relation to growth phase dependent dissolved oxygen (DO), absolute ABF scFv D1.3 and dry biomass concentration.

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Microbial Cell Factories

ISSN: 1475-2859

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