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Figure 1 | Microbial Cell Factories

Figure 1

From: Metabolic pathway engineering based on metabolomics confers acetic and formic acid tolerance to a recombinant xylose-fermenting strain of Saccharomyces cerevisiae

Figure 1

Schematic representation of xylose metabolic pathway in metabolically engineered S. cerevisiae strains. Abbreviations: BPGA, 1,3-bis phosphoglycerate; DHAP, dihydroxyacetonephosphate; E4P, erythrose-4-phosphate; FBP, fructose-1,6-bis phosphate; F6P, fructose-6-phosphate; GAP, glyceraldehyde-3-phosphate; Glycerol3P, glycerol-3-phosphate; G6P, glucose-6-phosphate; PEP, phosphoenol pyruvate; 6PG, 6-phosphogluconate; 2PGA, 2-phosphoglycerate; 3PGA, 3-phosphoglycerate; R5P, ribose-5-phosphate; Ru5P, ribulose-5-phosphate; S7P, sedoheptulose-7-phosphate; X5P, xylulose-5-phosphate. Enzymes are indicated by their gene assignment symbols: GND, 6-phosphogluconate dehydrogenase; SOL, 6-phosphogluconolactonase; TAL, transaldolase; TDH, glyceraldehydes-3-phosphate dehydrogenase; TKL, transketolase; RPE, ribulose-5-phosphate 4-epimerase; RKI, ribose-5-phosphate isomerase; XI, xylose isomerase; XK, xylulokinase; XDH, xylitol dehydrogenase; XR, xylose reductase; ZWF, glucose-6-phosphate dehydrogenase.

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