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Table 1 Parametric estimates and confidence intervals (α = 0.05) corresponding to equation (1) applied to the effect of formic and acetic acids on bacterial growth as optical density at 700 nm.

From: Evaluation of toxic effects of several carboxylic acids on bacterial growth by toxicodynamic modelling

   Formic acid Acetic acid
Parameters Bs Cb Ec Ln La Bs Cb Ec Ln La
  X m (AU) 6.40 ± 0.10 1.15 ± 0.01 2.67 ± 0.04 1.19 ± 0.01 0.79 ± 0.01 6.23 ± 0.13 1.01 ± 0.03 2.87 ± 0.06 0.97 ± 0.03 0.80 ± 0.02
growth model v m (AU h-1) 0.49 ± 0.03 0.18 ± 0.01 0.70 ± 0.04 0.27 ± 0.01 0.11 ± 0.01 0.51 ± 0.03 0.19 ± 0.02 0.69 ± 0.06 0.12 ± 0.01 0.11 ± 0.06
  λ (h) 3.62 ± 0.29 1.81 ± 0.21 0.91 ± 0.16 1.32 ± 0.11 0.94 ± 0.21 3.19 ± 0.40 1.40 ± 0.21 0.52 ± 0.21 0.77 ± 0.28 0.79 ± 0.18
  K x 0.87 ± 0.11 0.98 ± 0.03 0.81 ± 0.05 1.00 ± 0.01 0.83 ± 0.10 NS 0.37 ± 0.17 0.74 ± 0.24 1.00 ± 0.52 0.87 ± 0.11
effect on X m m x (mM) 35.95 ± 34.50 25.96 ± 1.02 18.23 ± 16.24 29.04 ± 1.30 5.59 ± 1.09 NS 15.78 ± 12.80 48.68 ± 16.29 71.35 ± 55.67 7.09 ± 6.92
  a x 29.01 (NS) 2.34 ± 0.26 22.14 ± 12.99 1.15 ± 0.07 2.44 ± 0.94 NS 0.99 ± 0.43 2.30 ± 0.40 1.10 ± 0.26 5.60 ± 5.51
  K v 0.99 ± 0.02 0.99 ± 0.01 1.02 ± 0.15 1.00 ± 0.01 0.98 ± 0.01 NS 0.98 ± 0.02 0.99 ± 0.03 1.00 ± 0.05 1.00 ± 0.02
effect on v m m v (mM) 35.89 ± 35.02 18.91 ± 2.18 18.36 ± 1.26 15.83 ± 1.71 3.80 ± 0.20 NS 16.94 ± 2.15 25.58 ± 2.40 63.46 ± 5.95 5.66 ± 0.28
  a v 23.92 (NS) 1.47 ± 0.25 2.12 ± 0.27 0.83 ± 0.10 3.11 ± 0.70 NS 1.00 ± 0.12 2.81 ± 0.97 2.47 ± 2.09 3.07 ± 0.87
  K λ NS 0.39 ± 0.33 NS 2.40 ± 2.73 NS NS NS NS NS NS
effect on λ m λ (mM) NS 4.10 ± 2.19 NS 61.10 ± 41.26 NS NS NS NS NS NS
  a λ NS 1.78 ± 1.09 NS 6.64 ± 5.38 NS NS NS NS NS NS
  p-value < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
  Bf 1.01 0.92 1.07 1.00 0.92 1.05 1.00 1.00 1.15 1.16
  Af 1.18 1.26 1.16 1.19 1.21 1.20 1.13 1.12 1.21 1.38
  R2adj 0.993 0.997 0.994 0.998 0.994 0.989 0.990 0.986 0.989 0.995
  1. NS: non significant. R2adj: adjusted coefficient of multiple determination. p-value from Fisher's F test (α = 0.05). B f and A f are the bias and accuracy factor, respectively. Keys for parameter and bacteria details are described in Tables 6 and 7, respectively.